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Research Fellow in Structural Biology of Cilia

Fixed term for 2 years

Project Title: Structural Biology of Cilia

Applications are invited for a Research Fellow post to be based in the group of Dr Joe Cockburn at the Astbury Centre for Structural Molecular Biology, University of Leeds, to perform structure/function studies on ciliary proteins. Cilia are the “antennae” of eukaryotic cells, sensing and integrating a wide variety of environmental signals (e.g light, molecules, proteins, and fluid flow). The aim of this work is to obtain a molecular understanding of key regulators of ciliary function, and how defects in these proteins lead to disease.

The project will require extensive knowledge of protein production and purification, biophysical characterisation of proteins and their complexes, and protein structure determination by X-ray crystallography. You must have a PhD in structural biology or a closely allied subject (or have a date set for examination). In addition, experience of performing structural studies by cryo-electron microscopy would be an advantage. You must be motivated and enthusiastic, and demonstrate a high level of relevant laboratory experience and technical competence. The ability to manage your time effectively and work under pressure and  as part of a team is essential, as well as having demonstrable expertise in protein X-ray crystallography as evidenced by publications, and have interests in structural cell biology.

The Astbury Centre for Structural Molecular Biology brings together over 60 research groups across the University of Leeds, from biological sciences, physics, chemistry, and mathematics, who share a common interest in understanding the molecular basis of living processes. The Centre is a major hub for structural biology research in the UK, with outstanding facilities and a vibrant, highly interdisciplinary research environment.

For further information please contact Dr Joe Cockburn or visit the group’s website:

Informal enquiries may be made to Dr Joe Cockburn, tel +44 (0)113 3430758, email

Interviews are expected to be held in February 2017

Click here for further information about working at the University of Leeds

Location:  Leeds - Main Campus
Faculty/Service:  Faculty of Biological Sciences
School/Institute:  School of Molecular & Cellular Biology
Category:  Research
Grade:  Grade 7
Salary:  £32,004 to £38,183 p.a.
Due to finding limitations the starting salary for this post will be £32,004 p.a.
Post Type:  Full Time
Contract Type:  Fixed Term (for 2 years)
Closing Date:  Monday 16 January 2017
Interview Date:  Thursday 23 February 2017
Reference:  FBSMB1092
Downloads:  Candidate Brief  

The closing date for this job opportunity has now passed, and applications are no longer being accepted for this position

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