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Principal Statistician

Do you have statistical experience in a medical environment and want to work for an Institute leading in clinical trials research and impacting clinical practice? Do you want to be part of a successful, highly talented, and multi-disciplinary team with international reach? Are you an enthusiastic, driven postgraduate with a major statistical qualification? Do you have considerable experience in complex intervention clinical trials in cancer or palliative care?

The Clinical Trials Research Unit (CTRU) is an international leader in the field of clinical trials. The Unit is one of the largest in the UK and conducts national and international randomised and early phase clinical trials in a variety of clinical fields. Our main aim is to support the challenge of changing clinical practice for the better and our past results and current work have already helped to do this. Our results inform the development of this specialised field of clinical research on a national and international level. Particularly, we specialise in complex phase III trials, efficient phase I/II trials, biomarker driven designs, seamless phase II/III designs, adaptive designs and the development and evaluation of complex interventions.

You will join a large, well-established group of statisticians to support the Unit’s work on clinical trials and be responsible for developing and leading a growing portfolio of early phase trials research evaluating novel therapies in cancer. You will work on internationally renowned trials designed to answer questions of real importance to enable further development of the clinical pathway, ultimately improving disease outcomes and patient care. Working with national leading clinicians you will develop phase I and II trials design to address disease-specific national research priorities, driving strategically aligned research with multiple stakeholders including clinicians, patients, the NHS, industry and charities. You will have opportunities to research, apply and develop statistical methodology, together with general consulting and training of health professionals. You will be involved in a wide range of statistical activities, including designing, conducting, analysing and publicising clinical trials, preparing grant applications and presenting at national and international conferences.

As Principal Statistician, you will provide the statistical strategic lead and supervision during the design and implementation for a number of phase I and II trials within the CTRU Early Phase Cancer Division. You will be a talented and dynamic individual with a postgraduate qualification, including a major statistical component, and an interest in the development and evaluation of cancer treatments within early phase trials. You will have the opportunity to drive implementation of novel early phase trial designs within an active portfolio of cancer trials. You will work closely, interactively and collaboratively with a multidisciplinary project team, including statisticians, programmers, clinicians, health economists, health service researchers and trial managers. As such you will need excellent communication and interpersonal and time management skills. You will have considerable experience in early phase clinical trials, project management and people management skills, together with a nationally recognised research profile in clinical trials and medical statistics.  

This role will provide you with an excellent opportunity to develop your career and national and international profile, enabling you to further broaden your expertise through methodological research within a supportive and stimulating environment with leadership opportunities; if applicable, you will also have the opportunity to register for a PhD.

To explore the post further or for any queries you may have, please contact: 

Dr Sarah Brown, Principal Statistician

Tel: +44 113 343 1472; Email:

Further Information

The University of Leeds is committed to providing equal opportunities for all and offers a range of family friendly policies. The University is a charter member of Athena SWAN and holds the Bronze award. The School of Medicine gained the Silver award in 2016.  We are committed to being an inclusive medical school that values all staff, and we are happy to consider job share applications and requests for flexible working arrangements from our employees.

Location:  Leeds - Main Campus
Faculty/Service:  Faculty of Medicine & Health
School/Institute:  Leeds Institute of Clinical Trials Research (LICTR)
Category:  Research
Grade:  Grade 8
Salary:  £40,792 to £48,677 p.a.
Working Time:  37.5 hours per week
Post Type:  Full Time
Contract Type:  Fixed Term (Open ended fixed funding for 36 months)
Release Date:  Monday 05 August 2019
Closing Date:  Monday 19 August 2019
Reference:  MHCTR1162
Downloads:  Candidate Brief  
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Athena Swan Bronze Award
Equality and Inclusion - Everyone Included, Everyone Involved
HR Excellence in Research