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Principal Statistician

Do you have statistical experience in a medical environment and want to work for an Institute leading in clinical trials research and impacting international clinical practice? Do you want to be part of a successful, highly talented, and multi-disciplinary team? Are you an enthusiastic, driven postgraduate with a major statistical qualification? 

The Clinical Trials Research Unit (CTRU) is an international leader in the field of clinical trials. The Unit is one of the largest in the UK and conducts national and international early phase and late phase clinical trials in a variety of clinical fields. Our main aim is to support the challenge of changing clinical practice for the better and our past results and current work have already helped to do this. Our results inform the academic development of this specialised field of clinical research on a national and international level. Particularly, we specialise in complex phase III trials, efficient phase I/II trials, biomarker-driven designs, seamless phase II/III designs, adaptive designs and the development and evaluation of complex interventions.

You will join a large, well-established group of statisticians to support the Unit’s work on clinical trials, specifically in the Leeds Cancer Research UK Clinical Trials Unit. You will be responsible for developing and leading a growing portfolio of early phase and/or late-phase trials research evaluating novel therapies and/or interventions in cancer. The Cancer Division includes major portfolios in haematological malignancies, the evaluation of radiotherapy as an intervention alone and in combination with pharmaceuticals in the treatment of a number of tumour sites, and a number of smaller developing portfolios. You will work on trials designed to answer questions of real importance to enable further development of the clinical pathway, ultimately improving disease outcomes and patient care. Working with national leaders you will develop trial designs to address disease-specific national research priorities, driving strategically aligned research with multiple stakeholders including clinicians, patients, the NHS, the NCRI, industry and charities. You will have opportunities to research, apply and develop statistical methodology, together with general consulting and training of health professionals. You will be involved in a wide range of statistical activities, including designing, conducting, analysing and publicising clinical trials, preparing grant applications and presenting at national and international conferences.

You will provide the statistical strategic lead and supervision during the design and implementation for a number trials within the CTRU Cancer Division. You will be a talented and dynamic individual with a postgraduate qualification, including a major statistical component, and an interest in the development and evaluation of cancer treatments within early phase and late phase trials. You will have the opportunity to drive implementation of novel trial designs within an active portfolio of cancer trials. You will work closely and collaboratively with a multidisciplinary project team, including statisticians, programmers, clinicians, health economists, health service researchers, data managers and trial managers. As such you will need excellent communication, interpersonal and time management skills. You will have considerable experience in clinical trials, project management and people management skills, together with a nationally recognised research profile in clinical trials and/or medical statistics.

This role will provide you with an excellent opportunity to develop your career, and national and international profile, enabling you to further broaden your expertise through methodological research within a supportive and stimulating environment with leadership opportunities; if applicable, you will also have the opportunity to register for a PhD.

To explore the post further or for any queries you may have, please contact: 

Dr Sarah Brown, Director of Early Phase Studies in Cancer Division

Tel: +44 (0)113 343 1472; Email:

Dr David Cairns, Director of Late Phase Studies in Cancer Division

Tel: +44 (0)113 343 1712; Email:       

Further Information

The University of Leeds is committed to providing equal opportunities for all and offers a range of family friendly policies. The University is a charter member of Athena SWAN and holds the Bronze award. The School of Medicine holds the Gold Award.  We are committed to being an inclusive medical school that values all staff, and we are happy to consider job share applications and requests for flexible working arrangements from our employees.

Location:  Leeds - Main Campus
Faculty/Service:  Faculty of Medicine & Health
School/Institute:  Leeds Institute of Clinical Trials Research (LICTR)
Category:  Research
Grade:  Grade 8
Salary:  £41,526 to £49,553 p.a.
Working Time:  100% at 37.5 hours per week
Post Type:  Full Time
Contract Type:  Fixed Term (open ended fixed funded for 36 months)
Release Date:  Monday 03 February 2020
Closing Date:  Wednesday 18 March 2020
Reference:  MHCTR1184
Downloads:  Candidate Brief  
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Athena Swan Bronze Award
Equality and Inclusion - Everyone Included, Everyone Involved
HR Excellence in Research